Selected Publications Prof. Dr. M. Sendtner

Wiese, S., Digby, M.R., Gunnerson, J.M., Götz, R., Pei, G., Holtmann, B. , Lowenthal, J.W. and M. Sendtner.
The anti-apoptotic protein ITA is essential for NGF-mediated survival of embryonic chick neurons.
Nature Neurosci. 2, 978-983, 1999.

Wiese, S., Pei, G., Karch, C., Troppmair, J., Holtmann, B., Rapp. U.R. and M. Sendtner.
Specific function of B-raf in mediating survival of embryonic motoneurons and sensory neurons.
Nature Neurosci. 4, 137-142, 2001.

Schweizer,U., Gunnersen, J., Karch, C., Wiese, S., Holtmann, B., Akira S. and M. Sendtner.
Conditional gene ablation of Stat3 reveals differential signalling requirements for motoneuron survival during development and in the adult after nerve injury.
J. Cell Biol. 156, 287-98, 2002.

Giess, R., Holtmann, B., Braga, M., Grimm, T., Müller-Myhsok, B., Toyka, K.V. and M. Sendtner
Early onset of severe familial ALS with a SOD-1 mutation: Potential impact of CNTF as a candidate modifier gene. Am.
J. Hum. Gen. 70, 1277-86, 2002.

Linker, R.A., Mäurer, M., Gaupp, S., Martini, R., Holtmann, B., Giess, R., Rieckmann, P., Lassmann, H., Toyka, K.V., Sendtner M. and R. Gold.
CNTF is a major protective factor in demyelinating CNS disease: a neurotrophic cytokine as modulator in neuroinflammation.
Nature Medicine 8, 620-624, 2002

Bömmel, H., Xie, G., Rossoll, G., Wiese, S., Jablonka, S., Boehm, T., and M. Sendtner.
Missense mutation in the tubulin-specific chaperone E (Tbce) gene in the mouse mutant “progressive motor neuronopathy”, a model of human motoneuron disease.
J. Cell Biol. 159, 563-569, 2002

Thoenen H. and M. Sendtner.
Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches.
Nat. Neurosci. 5, Suppl1, 1046-1050, 2002.

Rossoll, W., Jablonka, S., Andreassi, C., Kröning, A.-K., Karle, K., Monani, U.R. and M. Sendtner.
Smn, the spinal muscular atrophy determining gene product modulates axon growth and localization of ß-actin mRNA in growth cones of motoneurons.
J. Cell Biol. 163, 801-812, 2003.

Chittka, A., Arevalo, J.C., Rodriguez-Guzman, M., Perez, P., Chao, M.V. and M. Sendtner.
The p75NTR Interacting Protein SC1 Inhibits Cell Cycle Progression by Transcriptional Repression of Cyclin E.
J. Cell Biol. 164, 985-996, 2004.

Holtmann, B., S. Wiese, M. Samsam, K. Grohmann, D. Pennica, R. Martini and M. Sendtner.
Triple-knockout of CNTF, LIF and CT-1 defines cooperative and distinct roles of these neurotrophic factors for motoneuron maintenance and function.
'J. Neurosci. 25, 1778-1787, 2005.

Götz, R., Wiese, S., Takayama, S., Camarero, G.C., Rossoll, W., Schweizer, U., Troppmair, J., Jablonka, S., Holtmann, B., Reed, J.C., Rapp, U.R. and M. Sendtner.
Essential role of bag-1 for differentiation and survival of neural precursor cells.
Nat. Neurosci. 8, 1169-1178, 2005. ´

Barnabé-Heider, F.*, Wasylnka, J.A., Fernandes, K.J.L., Porsche, C., Sendtner, M., Kaplan, D.R. and Freda D. Miller.
An extrinsic cortical timer mechanism: evidence that embryonic neurons regulate the onset of cortical gliogenesis via cardiotrophin-1.
Neuron 48, 253-65, 2005